How do diseases develop?

How coronary artery diseases develop?

From Cleveland Clinic  

What is coronary artery disease?

Coronary artery disease is the narrowing or blockage of the coronary arteries caused by atherosclerosis. Atherosclerosis (sometimes called “hardening” or “clogging” of the arteries) is the buildup of cholesterol and fatty deposits (called plaque) on the inner walls of the arteries that restricts blood flow to the heart.
Without adequate blood, the heart becomes starved of oxygen and the vital nutrients it needs to work properly. This can cause chest pain called angina. When one or more of the coronary arteries are completely blocked, a heart attack (injury to the heart muscle) may occur.

• Get a closer look at your coronary arteries.

The process of coronary artery disease

1. Your coronary arteries are shaped like hollow tubes through which blood can flow freely. The walls of the coronary arteries are normally smooth and elastic.



2. Coronary artery disease starts when you are very young. Before your teen years, the blood vessel walls begin to show streaks of fat.



3. With coronary artery disease, as you get older, the fat builds up, causing slight injury to your blood vessel walls. In an attempt to heal the blood vessel walls, the cells release chemicals that make the blood vessel walls stickier. Other substances traveling through your blood stream, such as inflammatory cells, cellular waste products, proteins and calcium, begin to stick to the vessel walls. The fat and other substances combine to form a material called plaque.



4. Over time, with coronary artery disease, the inside of the arteries develop plaques of different sizes. Many of the plaque deposits are soft on the inside with a hard fibrous “cap” covering the outside. If the hard surface cracks or tears, the soft, fatty inside is exposed. Platelets (disc-shaped particles in the blood that aid clotting) come to the area, and blood clots form around the plaque.

5. This causes the artery to narrow even more. Sometimes, the blood clot breaks apart, and blood supply is restored.



6. In other cases, the blood clot may totally block the blood supply to the heart muscle, called a coronary thrombus or coronary occlusion - causing an acute coronary syndrome.

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The Leptospirosis Information Center

How quickly can an illness develop?

Human leptospirosis takes a while to incubate, and the normal range between exposure and illness is 3 to 14 days, although it can take up to 21 days. It's considered extremely unlikely that the illness would show earlier than 24 hours after exposure, even if the patient was otherwise unwell. In rare cases the incubation time can be very long (several weeks) but we normally assume that if there is no illness after 30 days then infection is either not present, or was subclinical.
Illness that develops within 12 hours of the exposure event would not be leptospiral in origin. Often infections that involve contaminated water can show illness very rapidly, caused by the effects of other unrelated bacteria and viruses in the water (such as E.coli or cryptosporidium) or from some chemicals, and while these would not in themselves normally be life-threatening, they can mask the later symptoms of leptospirosis.
The incubation time depends on the strain of bacteria involved, as some strains reproduce faster in human blood than others, but the main factor is the size of the 'inoculum' - the dose of bacteria that entered the patient during their exposure. Although it's perfectly possible to be infected from a single bacterium, in reality the illness develops because the rate that the bacteria are reproducing is faster than the patient's immune system can control. Bacteria grow by splitting in half, so one becomes two, two become four, and so on. If the patient received a large number of bacteria from the initial contact then the numbers in their bloodstream will be larger, and increase faster - hence the illness develops sooner.
It's very difficult to predict the incubation time in a patient, but in very general terms the concentration of bacteria in the inoculum will be important (water from a large clean river will have many times less bacteria per liter than urine direct from a rat) and the volume that enters the body (infection via small cuts to the skin usually involve very small volumes of liquid, but swallowing water after a fall into a lake will of course involve far more. The balance of course is that the situations where patients suffer a high-volume intake are usually those where the liquid has a low concentration (you are unlikely to fall into a tank of rat urine).
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COMMENTS;

As written above disease develops for years except bacteria caused diseases.  At age below 30 you still feel healthy because you do not feel any pain but the accumulation of chemicals from personal care products, junk foods, processed food, soft drinks, pollution from water and air are already high in your system.You did not give any attention to do anything for your body because nobody told you that, what you believe is that you are healthy. Toxins continue to accumulate and when you reach beyond age of 40 your body gives you alarm of high blood pressure, uric acid and sugar level. In some instances when the alarm signals the illness is already serious.

Question, can we live today without illness? The answer is no, nobody could escape because poisons or toxins are in everything that we eat, breath or use. Illness comes to us at different time, some get it early others also get it later depending on their health discipline.

Next question, can we live healthy today? The answer is yes although not perfectly, the solution is just basic, we must go back into using natural products. Avoid all things that have chemicals look for certified organic products. Look also for cheaper ones. If you love your body and wanted to live longer you must have budget for it.

Next question, how can we escape from toxins if all meats have chemicals? The answer is you must clean your body’s system every day. Drug medicine cannot be used because to ingest it every day is like killing yourself damaging your internal organs. You just look for best detoxification organic supplements.

Do also the simple steps to become healthy, open this page;

  http://healthwealth-rolssky.blogspot.com/2012/01/pillars-of-health.html
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